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human small cell lung cancer cell lines h146  (ATCC)


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    ATCC human small cell lung cancer cell lines h146
    Binding affinities of our designed compounds to Bcl-2 and Bcl-X L proteins in our FP-based assays and inhibition of cell growth in two cancer cell lines.
    Human Small Cell Lung Cancer Cell Lines H146, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1982 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human small cell lung cancer cell lines h146/product/ATCC
    Average 96 stars, based on 1982 article reviews
    human small cell lung cancer cell lines h146 - by Bioz Stars, 2026-03
    96/100 stars

    Images

    1) Product Images from "Design of Bcl-2 and Bcl-xL Inhibitors with Subnanomolar Binding Affinities Based Upon a New Scaffold"

    Article Title: Design of Bcl-2 and Bcl-xL Inhibitors with Subnanomolar Binding Affinities Based Upon a New Scaffold

    Journal: Journal of Medicinal Chemistry

    doi: 10.1021/jm300178u

    Binding affinities of our designed compounds to Bcl-2 and Bcl-X L proteins in our FP-based assays and inhibition of cell growth in two cancer cell lines.
    Figure Legend Snippet: Binding affinities of our designed compounds to Bcl-2 and Bcl-X L proteins in our FP-based assays and inhibition of cell growth in two cancer cell lines.

    Techniques Used: Binding Assay, Inhibition

    Binding affinities of our designed compounds to Bcl-2 and Bcl-X L proteins in FP-based assays and inhibition of cell growth in two small-cell lung cancer cell lines.
    Figure Legend Snippet: Binding affinities of our designed compounds to Bcl-2 and Bcl-X L proteins in FP-based assays and inhibition of cell growth in two small-cell lung cancer cell lines.

    Techniques Used: Binding Assay, Inhibition

    (A). Cell death induction by 20 and 21 in the H146 cancer cell line. Cells were treated for 24 h and cell death was analyzed by trypan blue assay. (B). Induction of cleavage of PARP and caspase-3 by 20 and 21 in the H146 cell line. Cells were treated for 24 h and caspase-3 and PARP were probed by western blotting.
    Figure Legend Snippet: (A). Cell death induction by 20 and 21 in the H146 cancer cell line. Cells were treated for 24 h and cell death was analyzed by trypan blue assay. (B). Induction of cleavage of PARP and caspase-3 by 20 and 21 in the H146 cell line. Cells were treated for 24 h and caspase-3 and PARP were probed by western blotting.

    Techniques Used: Western Blot



    Similar Products

    human small cell lung cancer cell lines h146  (ATCC)
    96
    ATCC human small cell lung cancer cell lines h146
    Binding affinities of our designed compounds to Bcl-2 and Bcl-X L proteins in our FP-based assays and inhibition of cell growth in two cancer cell lines.
    Human Small Cell Lung Cancer Cell Lines H146, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human small cell lung cancer cell lines h146/product/ATCC
    Average 96 stars, based on 1 article reviews
    human small cell lung cancer cell lines h146 - by Bioz Stars, 2026-03
    96/100 stars
    		  Buy from Supplier

    Image Search Results


    Binding affinities of our designed compounds to Bcl-2 and Bcl-X L proteins in our FP-based assays and inhibition of cell growth in two cancer cell lines.

    Journal: Journal of Medicinal Chemistry

    Article Title: Design of Bcl-2 and Bcl-xL Inhibitors with Subnanomolar Binding Affinities Based Upon a New Scaffold

    doi: 10.1021/jm300178u

    Figure Lengend Snippet: Binding affinities of our designed compounds to Bcl-2 and Bcl-X L proteins in our FP-based assays and inhibition of cell growth in two cancer cell lines.

    Article Snippet: Human small cell lung cancer cell lines H146 and H1417 were purchased from the American Type Culture Collection (ATCC) and were maintained in RPMI-1640 medium containing 10% FBS.

    Techniques: Binding Assay, Inhibition

    Binding affinities of our designed compounds to Bcl-2 and Bcl-X L proteins in FP-based assays and inhibition of cell growth in two small-cell lung cancer cell lines.

    Journal: Journal of Medicinal Chemistry

    Article Title: Design of Bcl-2 and Bcl-xL Inhibitors with Subnanomolar Binding Affinities Based Upon a New Scaffold

    doi: 10.1021/jm300178u

    Figure Lengend Snippet: Binding affinities of our designed compounds to Bcl-2 and Bcl-X L proteins in FP-based assays and inhibition of cell growth in two small-cell lung cancer cell lines.

    Article Snippet: Human small cell lung cancer cell lines H146 and H1417 were purchased from the American Type Culture Collection (ATCC) and were maintained in RPMI-1640 medium containing 10% FBS.

    Techniques: Binding Assay, Inhibition

    (A). Cell death induction by 20 and 21 in the H146 cancer cell line. Cells were treated for 24 h and cell death was analyzed by trypan blue assay. (B). Induction of cleavage of PARP and caspase-3 by 20 and 21 in the H146 cell line. Cells were treated for 24 h and caspase-3 and PARP were probed by western blotting.

    Journal: Journal of Medicinal Chemistry

    Article Title: Design of Bcl-2 and Bcl-xL Inhibitors with Subnanomolar Binding Affinities Based Upon a New Scaffold

    doi: 10.1021/jm300178u

    Figure Lengend Snippet: (A). Cell death induction by 20 and 21 in the H146 cancer cell line. Cells were treated for 24 h and cell death was analyzed by trypan blue assay. (B). Induction of cleavage of PARP and caspase-3 by 20 and 21 in the H146 cell line. Cells were treated for 24 h and caspase-3 and PARP were probed by western blotting.

    Article Snippet: Human small cell lung cancer cell lines H146 and H1417 were purchased from the American Type Culture Collection (ATCC) and were maintained in RPMI-1640 medium containing 10% FBS.

    Techniques: Western Blot